I have a 2003 Hayabusa that I use for sport-touring duties. It's decked out with hard bags, GPS, XM, Throttlemeisters, ZG ST windscreen. I've got about 52,000 miles on it, 46 states under her belt, and I've never had a problem with any kind of vibration at any rpm. I don't leave it at 4500 rpm either though. The *super* sweet spot is about 5100 rpm. Unfortunately, in 6th gear, that also translates to about 95.